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Subject: Cap-dependent endonuclease inhibitors (CENis) - NHRC
Solicitation Number: N0018926QB059
Notice Type: SOLICIT
NAICS: 541715
Set-Aside: No Set aside used
Notice Published: 05-26-26
Response Due: 05-28-26

Agency: Department of the Navy
Office: NAVSUP FLT LOG CTR NORFOLK
Contact: Brian Kinkade This email address is being protected from spambots. You need JavaScript enabled to view it. Ph: (771) 229-2412
Office Address: NORFOLK, VA 23511-3392
Place of Performance: Galveston, TX

Related Notices:

        05-15-26 SOLICIT

Click for official SAM (FBO) notice, additional information, and accompanying attachments

The preclinical development of Cap-dependent endonuclease inhibitors (CENi), a class of small molecules, as broad-spectrum antiviral therapeutics. The scope of this project includes all activities required to select lead CENi candidates, including in vitro and in vivo efficacy studies and characterization and optimization of lead compounds. This includes Research Support expertise regarding the preclinical development of cap-dependent endonuclease inhibitors (CENis) with viruses that require biosafety level 4 (BSL-4) containment to support the Naval Medical Research Command in Fort Detrick, MD. This work will be performed over a 36-month period.