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Subject: Measuring mouse body composition
Solicitation Number: 75N98026Q00471
Notice Type: PRESOL
NAICS: 334516
Set-Aside: Total Small Business
Notice Published: 05-29-26
Response Due: 06-09-26

Agency: Department of Health and Human Services
Office: NATIONAL INSTITUTES OF HEALTH
Contact: John Burton This email address is being protected from spambots. You need JavaScript enabled to view it.
Office Address: BETHESDA, MD 20892
Place of Performance: MD 20892


Click for official SAM (FBO) notice, additional information, and accompanying attachments

The National Institute of Diabetes and Digestive and Kidney Diseases requires an Whole Body Composition Analyzer to measure fat mass, lean mass, and body water in live mice. This system will replace an existing analyzer that is over 17 years old and no longer operational. The instrument provides rapid, non-invasive measurements in conscious animals without anesthesia, ensuring accurate and reproducible data. It will be shared across multiple laboratories and is required to support ongoing research in obesity, diabetes, and related metabolic disorders. The following product features/characteristics are required for this requirement: • Rapid scan time (~1–2 minutes per mouse) • No anesthesia requirement • High precision and reproducibility for fat and lean mass • Non-invasive, longitudinal measurement capability • Minimal operator variability • Validated performance in peer-reviewed metabolic research These features are essential for maintaining sympathetic tone and avoiding anesthetic-induced alterations in metabolic readouts, which is critical in acute drug response and metabolic studies.