Olink Explorer >5400
Subject: Olink Explorer >5400Solicitation Number: 75N98026Q00800Notice Type: SOLICITNAICS: 541380Set-Aside: No Set aside usedNotice Published: 07-15-26Response Due: 07-25-26Agency: Department of Health and Human ServicesOffice: NATIONAL INSTITUTES OF HEALTHContact: John Burton This email address is being protected from spambots. You need JavaScript enabled to view it.Office Address: BETHESDA, MD 20892Place of Performance: Bethesda, MD 20892
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Requirements: 2.0 BACKGROUND Our lab studies the role of inflammation/innate resistance and commensal microbiota in carcinogenesis, cancer progression and therapy of cancer. The following product features/characteristics are required for this requirement: Protein Coverage - Measures ~5,400+ human proteins simultaneously in a single workflow. Technology - Uses Proximity Extension Assay (PEA) with dual antibody recognition coupled to DNA barcoding and next-generation sequencing (NGS) readout. Sample input ? requires only 2 ul of plasma, serum, and other sample types Specificity - Reported 99.5% specificity with negligible cross-reactivity due to dual-recognition antibody design. Dynamic Range - Approximately 10 orders of magnitude (fg/mL to mg/mL), enabling detection of both low- and high-abundance proteins. Key strengths Very broad proteome coverage while maintaining antibody-based specificity. Excellent sensitivity for low-abundance circulating proteins (especially cytokines and signaling proteins). Extremely low sample-volume requirement. Highly standardized platform, making it attractive for epidemiology and multi-omics studies.